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Experimental Physics / Macromolecular Structure

Prof. Dr. Heinz-Jürgen Steinhoff

Fachbereich Physik
Universität Osnabrück
Barbarastrasse 7
D-49076, Osnabrück
Phone:
Fax:
email:
+49 541 969 2675 o. 2820
+49 541 969 2656
hsteinho@uni-osnabrueck.de

Our activities focus on the development of advanced electron paramagnetic resonance (EPR) methods, including site directed spin labelling, and their application to biomolecules and biomolecular complexes. The interpretation of the experimental data is done in the frame of molecular dynamics simulation methods with the goal to better understand the structure-dynamics-function relationship of proteins and nucleic acids.

  • Light sensitive proteins:
    • The signal transfer mediated by the sensory rhodopsin - transducer complex
    • Light induced electron transfer in the bacterial photosynthetic reaction center
  • Transmembrane transporters:
    • ABC-transporters MalFGK2, HisQMP2, Na/prolin transporter PutP
  • Folding of proteins:
    • Colicin A and its interaction with the cell membrane
  • Conformational dynamics of DNA and RNA

These activities are integrated in the Collaborative Research Center SFB 944.

PD. Dr. Armen Mulkidjanian

Fachbereich Physik
Universität Osnabrück
Barbarastrasse 7
D-49076, Osnabrück
Phone:
Fax:
email:
+49 541 969 2698
+49 541 969 2656
amulkid @ uni-osnabrueck.de

Molecular mechanisms and evolution of biological energy conversion:

from: Mulkidjanian et. al. TIBS 2009

 

Letzte Änderung: 27.07.2016 HJS